No, Kodi doesn't work well with IPv6 address.
In the log you can see it remove the brackets by mistake.
I believe it's a coding bug.
Below is the log:
2022-05-20 22:07:53.370 T:13455215 INFO <general>: Creating InputStream
2022-05-20 22:07:53.371 T:13455215 DEBUG <general>: ScanForExternalSubtitles: Searching for subtitles...
2022-05-20 22:07:53.372 T:13455215 DEBUG <general>: CurlFile::Open(0x70000b0f3cf8)
http://2001:da8:c000:1201:f816:3eff:fe09:940e/hls/
2022-05-20 22:07:53.372 T:13455215 DEBUG <general>: easy_acquire - Created session to
http://2001:da8:c000:1201:f816:3eff:fe09:940e
2022-05-20 22:07:53.372 T:13455215 DEBUG <general>: Curl:
ebug - TEXT: Closing connection -1
2022-05-20 22:07:53.372 T:13455215 ERROR <general>: CCurlFile::FillBuffer - Failed: URL using bad/illegal format or missing URL(3)
2022-05-20 22:07:53.372 T:13455215 ERROR <general>: CCurlFile::Open failed with code 0 for
http://2001:da8:c000:1201:f816:3eff:fe09:940e/hls/:
2022-05-20 22:07:53.373 T:13455215 ERROR <general>: GetDirectory - Unable to get http directory (
http://2001:da8:c000:1201:f816:3eff:fe09:940e/hls/)
2022-05-20 22:07:53.373 T:13427968 DEBUG <general>: CPlayerGUIInfo::InitCurrentItem(pvr://channels/tv/%e5%85%a8%e9%83%a8%e9%a2%91%e9%81%93/pvr.iptvsimple_461908148.pvr)
2022-05-20 22:07:53.373 T:13455215 ERROR <general>: GetDirectory - Error getting
http://2001:da8:c000:1201:f816:3eff:fe09:940e/hls/
2022-05-20 22:07:53.373 T:13455215 DEBUG <general>: ScanForExternalSubtitles: END (total time: 2 ms)
2022-05-20 22:07:53.373 T:13455215 INFO <general>: Creating Demuxer
2022-05-20 22:07:53.373 T:13455215 DEBUG <general>: ffmpeg[0x7fd4d7532440X]: [NULL] Opening 'http://2001:da8:c000:1201:f816:3eff:fe09:940e/hls/discovery.m3u8' for reading
2022-05-20 22:07:53.374 T:13455215 DEBUG <general>: ffmpeg[0x7fd4d7532440X]: [http] Setting default whitelist 'http,https,tls,rtp,tcp,udp,crypto,httpproxy,data'
2022-05-20 22:07:53.374 T:13455215 ERROR <general>: ffmpeg[0x7fd4d7532440X]: [tcp] Port missing in uri
2022-05-20 22:07:53.374 T:13442022 DEBUG <general>: Loading settings for pvr://channels/tv/%e5%85%a8%e9%83%a8%e9%a2%91%e9%81%93/pvr.iptvsimple_461908148.pvr
2022-05-20 22:07:53.374 T:13455215 DEBUG <general>: Error, could not open file
http://2001:da8:c000:1201:f816:3eff:fe09:940e/hls/discovery.m3u8